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pavlohrab/README.md

MSA

Website LinkedIn Google Scholar ORCID

Hi, I'm Pavlo Hrab

Computational biologist (PhD). Geneticist by training, bioinformatician by trade.

I work on microbial genomics, mostly genome mining: finding and characterizin biosynthetic gene clusters across genomes and metagenomes. I build the pipelines and tools that make that work reproducible, and I do the wet-lab side myself.

Currently doing postdoc at Wageningen University (Medema group).

Stack: R · Python · bash · Nextflow

Work: metagenomics · metatranscriptomics · phylogenetics · functional annotation · machine learning

Tools

  • BGCViz — Shiny app that cross-references BGC predictions from different tools using genomic coordinates, so you can see where they agree and where they don't
  • rRNADif — quantifies intragenomic 16S rRNA variation and places copies on a tree (docs)
  • ashelper — helper methods for antiSMASH and BiG-SCAPE output; standardizes BGC visualization for metagenomic data
  • hrmR — high-resolution melt (HRM) analysis for qPCR data
  • Mag_cleaning_pipeline — automated cleaning and QC of metagenome-assembled genomes
  • bigscape_pfam_explorer — explore BiG-SCAPE gene cluster families alongside their Pfam domain content
  • pfam_tools — utilities for Pfam-based functional annotation

BGCViz and rRNADif I wrote from scratch during my time in the Ostash group, which is why they live under that org.

Also contributed to metaWRAP (my commits).

Elsewhere

pavlohrab.com · LinkedIn · contact@pavlohrab.com

Pinned Loading

  1. BGCViz BGCViz Public

    Forked from ostash-group/BGCViz

    BGCViz - a shiny web app, which uses genomic coordinates of BGCs from different sources for a comprehensive comparison.

    R 3 1

  2. rRNADif rRNADif Public

    Forked from ostash-group/rRNADif

    rRNADif is a method to measure intragenomic 16S rRNA variability within the desired genome sequence against a chosen set of organisms. The app is calculating ML phylogenetic tree and uses mean/medi…

    Shell 1

  3. hrmR hrmR Public

    hrmR is a shiny app for HRM analysis, using RFU data. The app is tested for Cfx96 data, but any data should suffice, as long as the format is the same. Besides different plots, the app has also com…

    R 4

  4. process_fasta process_fasta Public

    A small collection of one-liners in a one bash script for fasta files processing.

    Shell 2 1

  5. GISAID_phylo GISAID_phylo Public

    Forked from MountainMan12/GISAID_phylo

    R 1