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Chrisolande/README.md
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🚀 Featured Projects

Statistical Inference

⛈️ Australian Rainfall Dynamics

Zero-inflated GLMM with hierarchical random effects

R glmmTMB Quarto

Zero-Inflated Gamma GLMM across 142k+ daily observations from 49 Australian locations. Covers model selection (M0–M6), DHARMa residual diagnostics, spatial heterogeneity estimation, and Markov chain temporal dependence analysis.

Complete

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🔄 Bayesian Time Series & Causal Inference

Scalable Bayesian inference for policy evaluation via INLA

R INLA Causal

Bayesian Structural Time Series for policy evaluation via INLA. Laplace approximation, causal identification assumptions, and interrupted time series design with a focus on efficient posterior computation and uncertainty quantification.

In Progress

🗺️ Spatial Hierarchical Bayesian Models

SPDE approximations for efficient spatial inference

R INLA Spatial

SPDE approximations for spatial GLMMs. CAR models, spatial random effects, and Bayesian hierarchical inference with geographic autocorrelation modelling and posterior spatial field estimation.

In Progress

Machine Learning & AI Engineering

🧬 Clinical Trial Agent

Multi-agent patient-to-trial matching pipeline

Python LangGraph PostgreSQL Docker

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🏥 Medical Research Assistant

Graph-based RAG pipeline for medical literature

Python LangChain NetworkX Streamlit

Complete
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🩺 Medical Report Generation

Agentic RAG pipeline for biomedical report synthesis

Python LangGraph DSPy

Complete
View Repo

🧠 Tech Stack

Statistical Computing & Inference

R
R
Statistical Analysis
Tidyverse
Tidyverse
Data Wrangling
ggplot2
ggplot2
Data Visualization
tidymodels
tidymodels
ML Framework
glmmTMB
Generalized Linear Mixed Models
INLA
Bayesian Inference
DHARMa
Residual Diagnostics
Git
Git
Version Control
Jupyter
Quarto
Reproducible Docs
PostgreSQL
PostgreSQL
Database

Machine Learning & AI Engineering

Python
Python
Primary Language
NumPy
NumPy
Scientific Computing
Pandas
Pandas
Data Manipulation
PyTorch
PyTorch
Deep Learning
TensorFlow
TensorFlow
Neural Networks
Scikit-learn
Scikit-learn
Machine Learning
Docker
Docker
MLOps
Git
Git
Version Control
Jupyter
Jupyter
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MongoDB
MongoDB
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  1. Medical-Research-Assistant Medical-Research-Assistant Public

    A comprehensive RAG pipeline combining knowledge graphs, vector search, and LLM generation for medical document analysis. Features semantic caching, advanced reranking, and modular architecture for…

    Python 13 2

  2. australian-rainfall-dynamics australian-rainfall-dynamics Public

    Hierarchical modeling of Australian rainfall using Zero-Inflated Gamma GLMMs. Addresses the "Zero-Mass" problem via a two-part logistic-Gamma framework. Features wind vector physics, Markov persist…

    R 2

  3. MedReportAI MedReportAI Public

    A biomedical research agent powered by Retrieval-Augmented Generation (RAG). It leverages PubMed and Tavily for knowledge retrieval, enabling accurate, context-aware medical report synthesis and ev…

    Python 2

  4. Causal-Inference-R- Causal-Inference-R- Public

    Working through Causal Inference in R, notes, code, and a Quarto book covering DAGs, IPW, doubly robust estimation, IV, DiD, RD, and sensitivity analysis.

    R

  5. clinical_trial_agent clinical_trial_agent Public

    An AI clinical matching agent that evaluates patient profiles against ClinicalTrials.gov data using a supervisor-driven LangGraph architecture and PostgreSQL persistence

    Python 2

  6. RAG RAG Public

    Collection of RAG techniques I've implemented so far. A part of an ongoing marathon to explore and document practical RAG strategies in NLP.

    Python 1