diff --git a/_quarto.yml b/_quarto.yml index bc3744a..aabddf4 100644 --- a/_quarto.yml +++ b/_quarto.yml @@ -29,6 +29,8 @@ website: href: wp3.qmd - text: "WP4: Intervention Development" href: wp4.qmd + - text: Events + href: events/index.qmd - text: Who We Are href: who-we-are.qmd - text: Outputs diff --git a/events/2026-03-18/index.qmd b/events/2026-03-18/index.qmd new file mode 100644 index 0000000..be42005 --- /dev/null +++ b/events/2026-03-18/index.qmd @@ -0,0 +1,80 @@ +--- +title: "Heterogeneity workshop / journal club" +description: "Agenda for the March 2026 workshop for Work Package 3." +date: "2026-03-18" +--- + +## Heterogeneity Workshop and Journal Club + +This file presents an overview of the talking points for the workshop, including relevant articles, measurement discussions, ideas, and suggestions. + +## Draft Agenda + +| Time | Topic | Presenter | +|:---|:---|:---| +| 11:00-12:00 | *Diabetes Heterogeneity Overview* | Daniel | +| | Introduction to the Workshop and Journal Club | Daniel | +| | Conceptual background: Different types of heterogeneity | Daniel | +| | Overview: Current approaches to heterogeneity in T2D and pre-diabetes | Christian / Mikkel S | +| 12:00-12:30 | Lunch Break | | +| 12:30-14:00 | Measurement Selection and Discussion | Kristina / David / Mikkel K / Jonas | +| 14:00-15:30 | Statistical Analysis and Group Work | Christian / Daniel | +| 15:30-16:00 | Plan for Journal Club series: dates, leads, topics | All | + +## Session Descriptions + +### 11:00-12:00 \| Diabetes Heterogeneity Overview + +A general introduction to diabetes heterogeneity and current discussions within the field, followed by an overview of three clustering methods: K-means, hierarchical clustering, and latent class analysis (LCA). + +### 12:00-12:30 \| Lunch Break + +Sandwiches from the cafeteria + +### 12:30-14:00 \| Measurement Selection and Discussion + +In this session we will review a proposed measurement list and discuss which measurements add important scientific value, consider participant burden, and assess feasibility across the different Steno Diabetes Centers. + +### 14:00-15:30 \| Statistical Analysis and Group Work + +In this session we will review statistical methods and how their algorithms work to explore heterogeneity. This will include a short presentation / some code-along / group exercises in R using a simple dataset to explore different clustering approaches. + +### 15:30-16:00 \| Plan for Journal Club + +To conclude we will discuss the best way to organise the Heterogeneity Journal club: Best day/time, which topics will we cover, who will take the lead on what. + +# Articles for discussion: + +- Ahlqvist et al. "Novel subgroups of adult-onset diabetes and their association with outcomes : a data-driven cluster analysis of six variables" + +- Wagner et al. "Beyond Glucose—Rethinking Prediabetes for Precision Prevention" + +- Dennis et al. "Precision medicine in type 2 diabetes: using individualized prediction models to optimize selection of treatment." + +- Udler et al. "Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis." + +- Deutsch et al. "Phenotypic and genetic classification of diabetes" + +- Dennis et al. "Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data" + +## Potential talking and discussion points: + +- Hard or soft clustering + +- Limitations of clustering and potential solutions + + - Temporal drift + + - Wagner: approximately 20% of type-2 diabetic patients change subgroup over a 5-year period. + + - What to do with people who don't fit clearly into one subtype? + + - Uncertainty about whether subgroups capture discrete pathologies + +- Clustering versus other approaches to map heterogeneity + +- Clustering using dynamic data (e.g. OGTT responses, continuous glucose monitoring, or physical activity monitoring) + + +- Clustering using dynamic data (e.g. OGTT responses, continuous + glucose monitoring, or physical activity monitoring) diff --git a/events/2026-09-24/index.qmd b/events/2026-09-24/index.qmd new file mode 100644 index 0000000..e43f720 --- /dev/null +++ b/events/2026-09-24/index.qmd @@ -0,0 +1,140 @@ +--- +title: "DP-Next Meeting 2026" +description: "A one-day meeting for all researchers involved in DP-Next, hosted at Aarhus University." +date: 2026-09-24 +toc: true +toc-location: right +toc-depth: 2 +--- + +# Welcome! + + + +:::: content-hidden +::: {.callout-important icon="false"} +## ✍ Registration is now open! + +Please follow this link to register \[insert link\] for the symposium and meeting. During registration, you can indicate whether you would like to give a short, 10 minute presentation on your work related to diabetes registers, demography, or related methods. + +If it turns out that you will not be able to attend after you have registered, please do not forget to cancel your registration. +::: +:::: + +## 1 year of DP-Next + +On the 1st of September we will reach the 1-year mark of the DP-Next project. We have achieved several early milestones and as the project is now in full swing we think it is a good opportunity to get together, share our experiences so far and make plans for the following years. + +The objective for the day is to share early results and experiences, to introduce ourselves to each other, sharing the various PhD and post-doc projects that form part of DP-Next. It will also be an opportunity to meet the members of the DP-Next Scientific Advisory Board and discuss our protocols and methods with them. + +During the day, we will also have the opportunity to present DP-Next to the wider researcher community at Steno Diabetes Center during one of the Steno Thursdays meetings. + +## Date and time + +::: callout-note +🗓 24 September 2026 + +🕰️ 10:00 - 17:00 +::: + +## Location + +::: {.callout-note icon="false"} +## 🏛️ Steno Diabtes Center Aarhus + +Verdensrummet AUD. A20 + +Palle Juul Jensens Boulevard 99 + +8200 Aarhus, Denmark +::: + +::: {.callout-note icon="false"} +## ️🖥️ Join us Online + +The seminar and meeting will also be streamed online for those who cannot join us in Aarhus. Please register through the link above and write 'online' in the Dietary Requirements field. + +Join us via Teams: [DP-Next Meeting \| Microsoft Teams](https://teams.microsoft.com/meet/347233238982094?p=nXgImEYyB0gj5UvrG5) + +Meeting ID: 347 233 238 982 094 + +Passcode: A5dc3Dx7 +::: + +## Join us for dinner + +::: {.callout-note icon="false"} +## 🍽️ Dinner + +After the meeting, you are welcome to join us for dinner at a restaurant in Aarhus C at 18:30. Please indicate whether you would like to attend when you register for the meeting on [Plan2Learn](https://rm.plan2learn.dk/kursusvalg.aspx?id=146365&catalog=13a4117b-f630-4889-9f77-56f41a39348e) +::: + +## Programme + ++-----------+-----------+--------------------------------------------+-----------------+ +| Start | End | Title | Speaker | ++===========+===========+============================================+=================+ +| *10:00* | *10:30* | *Coffee* | *-* | ++-----------+-----------+--------------------------------------------+-----------------+ +| 10:30 | 10:45 | Welcome and overview of DP-Next so far | Daniel Witte | ++-----------+-----------+--------------------------------------------+-----------------+ +| 10:45 | 11:00 | WP1: Progress so far and plans | Luke Johnston | ++-----------+-----------+--------------------------------------------+-----------------+ +| 11:00 | 11:15 | WP2: Progress so far and plans | Stine Byberg | ++-----------+-----------+--------------------------------------------+-----------------+ +| *11:15* | *11:30* | WP3: Progress so far and plans | Claus Bogh Juhl | ++-----------+-----------+--------------------------------------------+-----------------+ +| 11:30 | 11:45 | WP4: Progress so far and plans | Jane Østergaard | ++-----------+-----------+--------------------------------------------+-----------------+ +| 11:45 | 12:00 | Questions and Discussion | | ++-----------+-----------+--------------------------------------------+-----------------+ +| *12:00* | *12:30* | *Lunch* | *-* | ++-----------+-----------+--------------------------------------------+-----------------+ +| 12:30 | 14:00 | Short Presentations | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 12:30 | 12:40 | Short Presentation 1 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 12:40 | 12:50 | Short Presentation 2 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 12:50 | 13:00 | Short Presentation 3 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 13:00 | 13:10 | Short Presentation 4 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 13:10 | 13:20 | Short Presentation 5 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 13:20 | 13:30 | Short Presentation 6 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 13:30 | 13:40 | Short Presentation 7 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 13:40 | 13:50 | Short Presentation 8 | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 13:50 | 14:00 | Short Break and setup for Steno Thursdays | | ++-----------+-----------+--------------------------------------------+-----------------+ +| *14:00* | *15:00* | *DP-Next sessions at Steno Thursdays* | *-* | ++-----------+-----------+--------------------------------------------+-----------------+ +| 15:00 | 15:30 | Coffee and cake | | ++-----------+-----------+--------------------------------------------+-----------------+ +| 15:30 | 16:30 | Group work in parallel sessions: | | +| | | | | +| | | - Working together effectively | | +| | | | | +| | | - Using AI in research and data analysis | | +| | | | | +| | | - Other ideas.. | | ++-----------+-----------+--------------------------------------------+-----------------+ +| *16:30* | *17:00* | Plenary presentations of group work | *-* | ++-----------+-----------+--------------------------------------------+-----------------+ +| 17:00 | 17:00 | Final words and end of seminar | | ++-----------+-----------+--------------------------------------------+-----------------+ + +: Draft Program {tbl-colwidths="\[10,10,50,30\]" .striped} + +## Short Presentations + +| Name | Work Package | Affiliation | +|------|--------------|-------------| +| | | | + +: Short presentation presenter list {tbl-colwidths="\[30,50\]" .striped} + +## Speakers diff --git a/events/index.qmd b/events/index.qmd new file mode 100644 index 0000000..a94f89e --- /dev/null +++ b/events/index.qmd @@ -0,0 +1,10 @@ +--- +title: "Events for DP-Next" +listing: + contents: + - "2026-03-18" + - "2026-09-24" + sort: "date desc" +--- +This page contains a listing of events that DP-Next hosts or runs. Below is a list +of these events, ordered by date.