diff --git a/src/wp-includes/formatting.php b/src/wp-includes/formatting.php
index bd2d349fa20c1..cf2bbc8c7a1d6 100644
--- a/src/wp-includes/formatting.php
+++ b/src/wp-includes/formatting.php
@@ -2284,6 +2284,9 @@ function sanitize_title_with_dashes( $title, $raw_title = '', $context = 'displa
 	// Restore octets.
 	$title = preg_replace( '|---([a-fA-F0-9][a-fA-F0-9])---|', '%$1', $title );
 
+	// Convert multiplication sign and times entities to 'x'.
+	$title = str_replace( array( '×', '×', '×' ), 'x', $title );
+
 	if ( wp_is_valid_utf8( $title ) ) {
 		if ( function_exists( 'mb_strtolower' ) ) {
 			$title = mb_strtolower( $title, 'UTF-8' );
diff --git a/tests/phpunit/tests/formatting/sanitizeTitleWithDashes.php b/tests/phpunit/tests/formatting/sanitizeTitleWithDashes.php
index 8a2ee4f9d9fee..5292e2f202692 100644
--- a/tests/phpunit/tests/formatting/sanitizeTitleWithDashes.php
+++ b/tests/phpunit/tests/formatting/sanitizeTitleWithDashes.php
@@ -146,7 +146,39 @@ public function test_replaces_forward_slash() {
 	 * @ticket 19820
 	 */
 	public function test_replaces_multiply_sign() {
-		$this->assertSame( '6x7-is-42', sanitize_title_with_dashes( '6×7 is 42', '', 'save' ) );
+		$this->assertSame( '6x7-is-42', sanitize_title_with_dashes( '6×7 is 42', '', 'save' ), 'Multiplication sign (×) should be replaced with letter x' );
+	}
+
+	/**
+	 * @ticket 64284
+	 */
+	public function test_replaces_multiply_sign_with_spaces() {
+		$this->assertSame( 'iphone-12-x-256gb', sanitize_title_with_dashes( 'iPhone 12 × 256GB', '', 'save' ), 'Product title with multiplication sign and spaces should convert × to x' );
+		$this->assertSame( 'screen-1920-x-1080', sanitize_title_with_dashes( 'Screen 1920 × 1080', '', 'save' ), 'Screen dimensions with multiplication sign should convert × to x' );
+	}
+
+	/**
+	 * @ticket 64284
+	 */
+	public function test_replaces_times_html_entity() {
+		$this->assertSame( '6x7-is-42', sanitize_title_with_dashes( '6×7 is 42', '', 'save' ), 'HTML entity × should be replaced with letter x' );
+		$this->assertSame( 'product-5x10', sanitize_title_with_dashes( 'Product 5×10', '', 'save' ), 'HTML entity × without spaces should be replaced with letter x' );
+	}
+
+	/**
+	 * @ticket 64284
+	 */
+	public function test_replaces_times_numeric_entity() {
+		$this->assertSame( '3x4-equals-12', sanitize_title_with_dashes( '3×4 equals 12', '', 'save' ), 'Numeric HTML entity × should be replaced with letter x' );
+	}
+
+	/**
+	 * @ticket 64284
+	 */
+	public function test_replaces_multiply_sign_in_display_context() {
+		// Should work in display context too, not just 'save'.
+		$this->assertSame( '6x7', sanitize_title_with_dashes( '6×7', '', 'display' ), 'Multiplication sign should be replaced with x in display context' );
+		$this->assertSame( 'testx', sanitize_title_with_dashes( 'test×', '' ), 'Multiplication sign should be replaced with x when context is not specified' );
 	}
 
 	/**