diff --git a/internal/controller/datadogagent/feature/gpu/envvar.go b/internal/controller/datadogagent/feature/gpu/envvar.go
index 46940b287b..8213b2f35a 100644
--- a/internal/controller/datadogagent/feature/gpu/envvar.go
+++ b/internal/controller/datadogagent/feature/gpu/envvar.go
@@ -17,3 +17,6 @@ const NVIDIAVisibleDevicesEnvVar = "NVIDIA_VISIBLE_DEVICES"
 
 // DDPatchCgroupPermissionsEnvVar is the name of the system-probe gpu_monitoring module cgroup permissions patch knob
 const DDPatchCgroupPermissionsEnvVar = "DD_GPU_MONITORING_CONFIGURE_CGROUP_PERMS"
+
+// DDEnableEBPFProbesEnvVar is the name of the system-probe gpu_monitoring module eBPF probes enablement knob
+const DDEnableEBPFProbesEnvVar = "DD_GPU_MONITORING_ENABLE_EBPF_PROBES"
diff --git a/internal/controller/datadogagent/feature/gpu/feature.go b/internal/controller/datadogagent/feature/gpu/feature.go
index ad2a949a1d..99f34d9a2c 100644
--- a/internal/controller/datadogagent/feature/gpu/feature.go
+++ b/internal/controller/datadogagent/feature/gpu/feature.go
@@ -127,6 +127,21 @@ func configureSystemProbe(managers feature.PodTemplateManagers) {
 	// add the env var to the core agent as well, to prevent config mismatches in runtime
 	managers.EnvVar().AddEnvVarToContainer(apicommon.CoreAgentContainerName, enableSPEnvVar)
 
+	// In privileged mode the eBPF probes are disabled, as GPU monitoring relies on
+	// the privileged host access rather than the eBPF probes.
+	disableEBPFProbesEnvVar := &corev1.EnvVar{
+		Name:  DDEnableEBPFProbesEnvVar,
+		Value: "false",
+	}
+
+	// disable the eBPF probes in system-probe
+	managers.EnvVar().AddEnvVarToContainer(apicommon.SystemProbeContainerName, disableEBPFProbesEnvVar)
+
+	// add the env var to the core agent as well, so both containers agree that the
+	// eBPF probes are disabled and the core GPU check does not poll a system-probe
+	// module that has the probes turned off
+	managers.EnvVar().AddEnvVarToContainer(apicommon.CoreAgentContainerName, disableEBPFProbesEnvVar)
+
 	// annotations
 	managers.Annotation().AddAnnotation(common.SystemProbeAppArmorAnnotationKey, common.SystemProbeAppArmorAnnotationValue)
 
diff --git a/internal/controller/datadogagent/feature/gpu/feature_test.go b/internal/controller/datadogagent/feature/gpu/feature_test.go
index 6824e6640d..3ae8a55819 100644
--- a/internal/controller/datadogagent/feature/gpu/feature_test.go
+++ b/internal/controller/datadogagent/feature/gpu/feature_test.go
@@ -193,6 +193,10 @@ func Test_GPUMonitoringFeature_Configure(t *testing.T) {
 				Name:  DDEnableGPUProbeEnvVar,
 				Value: "true",
 			},
+			{
+				Name:  DDEnableEBPFProbesEnvVar,
+				Value: "false",
+			},
 			{
 				Name:  NVIDIAVisibleDevicesEnvVar,
 				Value: "all",
@@ -216,6 +220,10 @@ func Test_GPUMonitoringFeature_Configure(t *testing.T) {
 				Name:  DDEnableGPUProbeEnvVar,
 				Value: "true",
 			},
+			{
+				Name:  DDEnableEBPFProbesEnvVar,
+				Value: "false",
+			},
 			{
 				Name:  common.DDSystemProbeSocket,
 				Value: common.DefaultSystemProbeSocketPath,